Result活動実績

学会発表（国際学会）

2023

• 2023/11/3-5. SITC 2023 San Diego: the 38th Annual Meeting, Poster, Yukari Kobayashi, Koji Nagaoka, PhD, Sachiko Okamoto, Kazuhiro Kakimi, Concurrent identification of true neoantigens and neoantigen-specific T cells by scRNA-Seq and　scTRC-Seq.
• 2023/11/3-5. SITC 2023 San Diego: the 38th Annual Meeting, Poster, Koji Nagaoka, Yukari Kobayashi, Hiroto Katoh, Tomoko Saito, Yoshikazu Totsuka, Kazuyoshi Takeda, Shumpei Ishikawa, Kazuhiro Kakimi. scTCR/RNA-Seq identifiy two exhausted T cell subsets in neoantigen-specific CD8+ T cells.

2022

• 2022/1/9. Best of SABCS KYOTO 2022. ONLINE. Kazuhiro Kakimi. Basic Principles of Cancer Immunotherapy.

2021

• 2021/4/10. AACR2021 VIRTUAL MEEING、Poster Presentation. Changbo Sun, Koji Nagaoka, Akihiro Hosoi, Yukari Kobayashi, Jun Nakajima, Kazuhiro Kakimi. Neoantigen vaccine plus CD38 blockade suppress the proliferation of murine cold lung cancer LLC1.
• 2021/11/10-14. SITC2021 Walter E. Washington Convention Center in Washington, D.C. and virtually. Poster Presentation. Yoshihiro Kushihara, Yukari Kobayashi, Koji Nagaoka, Kazuhiro Kakimi. Possibility of immunotherapy for the glioblastoma patients with O6-methyl-guanine DNA methyltransferase (MGMT) expression or promoter unmethylated.
• 2021/11/10-14. SITC2021 Walter E. Washington Convention Center in Washington, D.C. and virtually. Poster Presentation. Yukari Kobayashi, Koji Nagaoka, Kaori Kubo, Toshikazu Nishie, Sachiko Okamoto, Tatsuji Enoki, Jun-ichi Mineno, Yasuyoshi Sato, Shunji Takahashi, Jun Nakajima, Kazuhiro Kakimi. A cloning and expression system of the neoantigen-specific TCRs from tumor-infiltrating lymphocytes by single-cell sequencing of paired TCRα and TCRβ chains.
• 2021/11/10-14. SITC2021 Walter E. Washington Convention Center in Washington, D.C. and virtually. Poster Presentation. Changbo Sun, Koji Nagaoka, Yukari Kobayashi, Jun Nakajima, Kazuhiro Kakimi. Exploiting tumor neoantigen-targeted immunotherapy in immunologically hot versus cold murine lung cancer models.
• 2021/11/10-14. SITC2021 Walter E. Washington Convention Center in Washington, D.C. and virtually. Poster Presentation. Koji Nagaoka, Changbo Sun, Yukari Kobayashi, Kazuhiro Kakimi. A murine gastric cancer YTN16 model for the rational design of combination immunotherapy.

2020

• 2020/7/23. AACR2020 VIRTUAL ANNUALMEEING II Virtual Minisymposium. Kazuhiro Kakimi. Autologous γδ T cell therapy for treatment-refractory non-small-cell lung cancer: An open-label, single-arm, multicenter, phase II study
• 2020/7/23. AACR2020 VIRTUAL ANNUALMEEING II、Poster Presentation. Yasuyoshi Sato, Ikuo Wada, Akihiro Hosoi, Yukari Kobayashi, Koji Nagaoka, Takahiro Karasaki, Hirokazu Matsushita, Koichi Yagi, Hiroharu Yamashita, Shunji Takahashi, Yasuyuki Seto, Kazuhiro Kakimi. Novel immunological classification of gastric cancer by integrative analysis,
• 2020/7/23. AACR2020　VIRTUAL ANNUALMEEING II、Poster Presentation. Masataka Shirai, Koji Nagaoka, Kiyomi Taniguchi, Changbo Sun, Akihiro Hosoi, Kazuhiro Kakimi. Single-cell RNA-Seq identified an immunosuppressive IL-17 producing tumor-infiltrating T cells in murine gastric tumor model,
• 2020/7/23. AACR2020　VIRTUAL ANNUALMEEING II、Poster Presentation. Koji Nagaoka, Takayuki Kanaseki, Changbo Sun, Akihiro Hosoi, Serina Tokita, Kazuhiro Maejima, Masashi Fujita, Hidewaki Nakagawa, Toshihiko Torigoe, Kazuhiro Kakimi. To identify neoantigens relevant to anti-tumor activity is challenging even with NGS-based prediction combined with MHC ligandome profiling,
• 2020/8/17-19. Keystone Symposia: eSymposia. Koji Nagaoka, Masataka Shirai, Kiyomi Taniguchi, Akihiro Hosoi, Changbo Sun, Yukari Kobayashi and Kazuhiro Kakimi. Deep-immunophenotyping at the single-cell level identifies a combination of anti-IL-17 and checkpoint blockade as an effective treatment in a preclinical model of data-guided personalized immunotherapy.

2019

• 2019/2/2. The 2nd International Cancer Research Symposium of Training Plan for Oncology Professionals、Tennouji-ku,Osaka,Japan/Sheraton Miyako Hotel Osaka "Yamato-no-Ma" Kazuhiro Kakimi. Cancer immunotherapy :Harnessing our immune system to fight against cancer
• 2019/6/6-7. The 26th International Symposium on Molecular Cell Biology of Macrophages MMCB2019、Bunkyo-Ku, Tokyo（Ito International Research Center)Koji Nagaoka, Akihiro Hosoi, Changbo Sun, Kiyomi Taniguchi, Masataka Shirai, Kazuhiro Kakimi. Early activation of myeloid cells is required for the CD8+ T-cell dependent anti-tumor immunity
• 2019/9/9. 2019 World Conference Lung Cancer (IASLC)、Barcelona,Spain. T. Karasaki, Y. Kobayashi, A. Shinozaki-Ushiku, C. Konoeda, K. Kitano, K. Nagayama, M. Sato, A. Hosoi, K. Kakimi, J. Nakajima. P2.04-55 TUMOR SPPEAD THROUGH AIR SPACES IS ASSOCIATED WITH THE NON-INFLAMED IMMUNE MICROENVIRONMENT IN LUNG SQUAMOUS CELL CARCINOMA

2018

• 2018/4/16. AACR(American Association for Cancer Research) Annual Meeting 2018、McCormick Place North/South Chicago, Illinois. Akihiro Hosoi, Hirokazu Matsushita, Kazuyoshi Takeda, Ryuji Suzuki, Kazuhiro Kakimi. Diversity evenness of TCR repertoire in the tumor and periphery reflects antitumor activity and immune-related adverse events,respectively
• 2018/4/18. AACR(American Association for Cancer Research) Annual Meeting 2018、McCormick Place North/South Chicago, Illinois. Hirokazu Matsushita, Kosei Hasegawa, Katsutoshi oda, Shogo Yamamoto, Kayo Asada, Akira Yabuno, Akira Nishijima, Takahiro krasaki, Yuji Ikeda, Keiichi Fujiwara, Hiroyuki Aburatani, Kazuhito Kakimi. Neoantigen load and HLA-class I expression characterize a subset of HR-proficient high-grade serous ovarian carcinomas with favorable prognosis and T cell-inflamed phenotype.
• 2018/6/27. THE 45th NAITO CONFERENCE ON Immunological and Molecular Bases for Cancer Immunotherapy 、SAPPORO, Japan Akihiro HOSOI, Hirokazu MATSUSHITA, Kazuhiro KAKIMI, Shoji IKEDA. Diversity evenness of TCR repertoire is associated with anti-tumor immunity and immune-related adverse events
• 2018/6/27. THE 45th NAITO CONFERENCE ON Immunological and Molecular Bases for Cancer Immunotherapy 、SAPPORO, Japan. Yukari KOBAYASHI, Kosuke ODAIRA, Kaori KAMBARA, Nao FUJIEDA, AKihiro HOSOI, Koji NAGAOKA, Hirokazu MATSUSHITA, Kazuhiro KAKIMI. Detection of neoantigen-reactive T cell response in mice and human
• 2018/6/28 THE 45th NAITO CONFERENCE ON Immunological and Molecular Bases for Cancer Immunotherapy 、SAPPORO, Japan. Kazuhiro KAKIMI 【Session D, New Technologies in Canser Research】 An Immunogram for the cancer-immunity cycle
• 2018/6/28. THE 45th NAITO CONFERENCE ON Immunological and Molecular Bases for Cancer Immunotherapy 、SAPPORO, Japan. Hirokazu MATSUSHITA, Kosei HASEGAWA, Kazuhito KAKIMI. Neoantigen burden and HLA -class I experession difine a subgroup of HR-proficent high-grade serous ovarian carcinomas with T-cell-inflamed phenotype and better prognosis
• 2018/6/28. THE 45th NAITO CONFERENCE ON Immunological and Molecular Bases for Cancer Immunotherapy 、SAPPORO, Japan. Yasuyoshi SATO, Hirokazu MATSUSHITA, Kazuhito KAKIMI, Yasuyuki SETO. Phase I trial of autologous tumor lysate-pulsed dendritic cell vaccination therapy after resection of stage IIA(T2N0,T3N0)esophageal cancer
• 2018/6/28. THE 45th NAITO CONFERENCE ON Immunological and Molecular Bases for Cancer Immunotherapy 、SAPPORO, Japan. Koji NAGAOKA, Akihiro Hosoi, Tamaki IINO, Hirokazu MATSUSHITA, Kazuhiro KAKIMI. Dendritic cell vaccines induce phenopically,metabolically and functionally distinct antigen specific memory CD8⁺ T cells from those by peptide vaccines
• 2018/6/28. THE 45th NAITO CONFERENCE ON Immunological and Molecular Bases for Cancer Immunotherapy 、SAPPORO, Japan. Kosuke ODAIRA, Ikuo WADA, Hitokazu MATSUSHITA, Kazuhiro KAKIMI, Daisuke NOGUCHI. Integrated analysis of tumor-microenvironment (TIME) and tumor infilrating cells in gastric cancer.
• 2018/9/25. IASLC 19th World Conference on Lung Cancer、Tronto, Canada.T.Karasaki, K.Kitano, K.Nagayama, J.Nitadori, M.Sato, M.Anraku ,K.Kakimi, J.Nakajima. DIFFERENCE OF TUMOR MUTATIONAL BURDEN IS ASSOCIATED WITH DISTINCT IMMUNE MICROENVIROMENT IN THE T-CELL-INFLAMED LUNG ADENOCARCINOMA

2017

• 2017/2/11. The 32nd Nagoya International Cancer Treatment Symposium、Nagoya, Japan (Invited, Symposium). Kazuhiro Kakimi. An Immunogram for the Cancer Immunotherapy
• 2017/2/23. ASCO-SITC Clinical Immuno-Oncology Symposium、Orlando. Yasuyoshi Sato, Hirokazu Matsushita, Kazuhiko Mori, Kazuhiro Kakimi and Yasuyuki Seto. Safety, efficacy and immunogenicity of autologous tumor lysate-pulsed dendritic cell vaccination therapy after resection of stage IIA (T2N0, T3N0) esophageal cancer: A phase I trial
• 2017/4/3. AACR(American Association for Cancer Research) Annual Meeting 2017、Washington Convention Center. Hirokazu Matsushita, Kosei Hasegawa, Katsutoshi Oda, Shogo Yamamoto, Akira Nishijima, Yuichi Imai, Kayo Asada, Yuji Ikeda, Takahiro Karasaki, Keiichi Fujiwara, Hiroyuki Aburatani, Kazuhiro Kakimi. Neoantigen frequency as an independent prognostic factor in patients with clear ovarian carcinoma(CCOC)
• 2017/4/4. AACR(American Association for Cancer Research) Annual Meeting 2017、Washington Convention Center. Koji Nagaoka, Akihiro Hosoi,Tamaki Iino, Hirokazu Matsushita, Kazuhiro Kakimi. Advantage of dendrituc cells for the therapeutic cancer vaccine
• 2017/6/23. The 36th Sapporo Internatonal Cancer Symposium, Sapporo, Japan (Royton Sapporo) Kazuhiro Kakimi. An Immunogram for the Cancer-Immunity Cycle
• 2017/9/22, Cold Spring Harbor Asia conferences、Suzhou, China(Suzhou Dushu Lake Conference Center) Kazuhiro Kakimi. An immunogram for the cancer-immunity cycle-Towards personalized immunotherapy
• 2017/10/13. JDDW(Japan Digestive Disease Week) 2017 FUKUOKA、Fukuoka. The Best Presenter Award in International Session. I. Wada, K. Odaira, K. Kakimi. Immunological analysis of the tumor infiltrating lymphocytes of the advanced gastric cancer
• 2017/10/15. IASLC(INTERNATIONAL ASSOCIATION FOR THE STUDY OF LUNG CANCER) 18TH WORLD CONFERENCE ON LUNG CANCER. Yokohama, Japan. T. Karasaki
• 2017/10/16. IASLC(INTERNATIONAL ASSOCIATION FOR THE STUDY OF LUNG CANCER) 18TH WORLD CONFERENCE ON LUNG CANCER、Yokohama, Japan. T. Karasaki, K. Nagayama, K. Fukumoto, K. Kitano, J. Nitadori, M. Sato, M. Anraku, A. Hosoi, H. Matsushita, K. Kakimi, J. Nakajima. ASSESSMENT OF CANCER IMMUNITY STATUS IN EACH PATIENT USING IMMUNOGRAM

2016

• 2016/3/4. 2016 International Biomedical Interface Symposium、Taipei, Taiwan (Invited) Kazuhiro Kakimi. Towards personalized cancer immunotherapy
• 2016/4/2. 2nd International Symposium of Lymphedema Surgery and Breast Reconstruction、Tokyo, Japan (Invited) Kazuhiro Kakimi. Cancer Immunity Cycle
• 2016/10/28. 2016 International Symposiumu for Recent Advances in Cell Therapy and 3rd Annual Meeting of Taiwan Association for Cell Therapy、Taipei, Taiwan(Invited, Symposium) Kazuhiro Kakimi. Personalized Cancer Immunotherapy
• 2016/12/7. IASLC(INTERNATIONAL ASSOCIATION FOR THE STUDY OF LUNG CANCER) 17TH WORLD CONFERENCE ON LUNG CANCER、Vienna, Austria. T. Karasaki, K. Nagayama, H. Kuwano, J. Nitadori, M. Sato, M. Anraku, H. Mtatsushita, Y. Morishita, K. Kashiwada, M. Takazawa, O. Ohara, K. Kakimi, J. Nakajima. Immunogram for Cancer-Immunity Cycle towards Personalized Immunotherapy of Lung Cancer

2015

• 2015/7/10. ICCIM2015 (International Conference of Cancer Immunotherapy and Macrophages 2015)、Tokyo Japan. Kazuhiro Kakimi. CTL-therapy induced Tumor immunosuppressive Environment
• 2015/7/9. ICCIM2015 (International Conference of Cancer Immunotherapy and Macrophages 2015)、Tokyo Japan. Koji Nagaoka, Tamaki Iino, Akihiro Hosoi, Manami Miyai, Hirokazu Matsushita, Kazuhiro Kakimi. Most of the CD8+ tumor-infiltrating lymphocytes are reactive to tumors in spontaneously regressing or progressing murine gastric cancer
• 2015/7/9. ICCIM2015 (International Conference of Cancer Immunotherapy and Macrophages 2015)、Tokyo Japan. Takuya Takahashi, Kosuke Odaira, Kaori Kambara, Nao Fujieda, Takamichi Izumi, Yukari Kobayashi, Hirokazu Matsushita, Kazuhiro Kakimi. Galectin-9 and Tim-3 interaction constrains Vγ9Vδ2 T cell-based immunotherapy
• 2015/7/9. ICCIM2015 (International Conference of Cancer Immunotherapy and Macrophages 2015)、Tokyo Japan. Akihiro Hosoi, Manami Miyai, Tamaki Iino, Hirokazu Matsushita, ShingoKikugawa, Paul Horton, Osamu Ohara, Kazuhiro Kakimi. Immunogenicity and cross-reactivity of tumor-specific mutated-antigens (neoantigens) identified by MHC-binding prediction
• 2015/7/9. ICCIM2015 (International Conference of Cancer Immunotherapy and Macrophages 2015)、Tokyo Japan. Kazuhiro Kakimi, Horokazu Matsushita, Taku Aoki, Kiyoshi Hasegawa, Norihiro Kokudo. Adjuvant combination therapy with gemcitabine and autologous γδ T cell transfer in patients with curatively resected pancreatic cancer
• 2015/7/9. ICCIM2015 (International Conference of Cancer Immunotherapy and Macrophages 2015)、Tokyo Japan. Kazuhiko Mori, Hirokazu Matsushita, Kazuhiro Kakimi, Yasuyuki Seto. A pilot study of DCF therapy (docetaxel, cisplatin, and 5-fluorouracil combination chemotherapy) followed by autologous γδ T cell transfer therapy for the treatment of advanced esophageal cancer.
• 2015/7/9. ICCIM2015 (International Conference of Cancer Immunotherapy and Macrophages 2015)、Tokyo Japan. Kosuke Odaira, Hirokazu Matsushita, Ikuo Wada, Yasuyuki Seto, Nao Fujieda, Yukari Kobayashi, Kazuhiro Kakimi. Expression of immune-checkpoint molecules on tumor infiltrating lymphocytes in patients with gastric cancer
• 2015/7/9. ICCIM2015 (International Conference of Cancer Immunotherapy and Macrophages 2015)、Tokyo Japan. Yukari Kobayashi, Kosuke Odaira, Nao Fujieda, Hirokazu Matsushita, Tohru Nakagawa, Haruki Kume, Daisuke Yamada, Yukio Homma, Kazuhiro Kakimi. Immunomodulatory effects of molecular targeted agents on peripheral immune effector cells in metastatic renal cell carcinoma.
• 2015/7/9. ICCIM2015 (International Conference of Cancer Immunotherapy and Macrophages 2015)、Tokyo Japan. Nao Fujieda, Junichiro Futami, Kosuke Odaira, Yukari Kobayashi, Hirokazu Matsushita, Kazuhiro Kakimi. A fluorescent multiplexed bead-based suspension array for simultaneous detection of antibodies against tumor antigens.
• 2015/7/9. ICCIM2015 (International Conference of Cancer Immunotherapy and Macrophages 2015)、Tokyo Japan. Manami Miyai, Shingo Eikawa, Akihiro Hosoi, Tamaki Iino, Hirokazu Matsushita, Midori Isobe, Akiko Uenaka, Heiichiro Udono, Jun Nakajima, Eiichi Nakayama, Kazuhiro Kakimi. The detection and tracking of NY-ESO-1-specific CD8+ T cells by next generation sequencing of human TCRB CDR3 rearrangements.
• 2015/7/9. ICCIM2015 (International Conference of Cancer Immunotherapy and Macrophages 2015)、Tokyo Japan. Hirokazu Matsushita, Manami Miyai, Yusuke Sato, Tohru Nakagawa, Haruki Kume, Seishi Ogawa, Yukio Homma, Kazuhiro Kakimi. Expression of candidate neoantigens in ccRCC patients and its implication on prognosis
• 2015/7/9. ICCIM2015 (International Conference of Cancer Immunotherapy and Macrophages 2015)、Tokyo Japan. Koji Kurose, Yoshihiro Ohue, Hisashi Wada, Shinsuke Iida, Takashi Ishida3, Takashi Kojima, Toshihiko Doi, Susumu Suzuki, Midori Isobe, Takeru Funakoshi, Kazuhiro Kakimi, Hiroyoshi Nishikawa, Heiichiro Udono, Mikio Oka, Ryuzo Ueda, Eiichi Nakayama. Phase Ia study of FoxP3+ CD4 Treg depletion by infusion of a humanized anti-CCR4 antibody, KW-0761, in cancer patients

2014

• 2014/11/7-9, SITC Annual Meeting2014, National Harbor, MD, USA. Kazuhiro Kakimi, Hirokazu Matsushita, Yutaka Enomoto,　Tohru　Nakagawa,　Haruki　Kume,　Yukio　Homma.　Autologous　tumor　lysate-loaded　dendritic　cell　vaccination combined with Sunitinib for metastatic renal cell carcinoma.

2013

• 2013/4/6-10, AACR　Annual Meeting 2013、Washington DC, USA, Kazuhiro Kakimi, Hirokazu Matsushita, Akihiro Hosoi, Ryuji Maekawa, and Osamu Ohara. Killing and IFN-γ-dependent G1 cell cycle arrest is the mechanism of regulation of tumor growth by Cytotoxic T Lymphocytes.
• 2013/9/30-10/2, 21st Annual cancer research Institute International cancer Immunotherapy Symposium. Cancer Immunotherapy 2013: Dynamics of Host-Tumor Interaction. Hirokazu Matsushita, Akihiro Hosoi, Satoshi Ueha, Jun Abe, Michio Tomura, Ryuji Maekawa, Osamu Ohara, Kazuhiro Kakimi, Killing and IFN-γ-dependent G1 cell cycle arrest is the mechanism of regulation of tumor growth by cytotoxic T lymphocytes.

2012

• 2012/3/31-4/4, The 2012 AACR Annual meeting in Chicago, IL, USA, Kazuhiro Kakimi, Akihiro Hosoi, Shuichi Noji, Hirokazu Matsushita, Kazuyoshi Takeda. Targeting spatio-temporal expression of CD137 on tumor-specific cytotoxic T lymphocytes as a novel strategy for agonistic antibody therapy
• 2012/8/22-26, 11th Asian Congress of Urology, Pattaya, Thailand, Yutaka Enomoto, Haruki Kume, Hiroshi Fukuhara, Tetsuya Fujimura, Motofumi Suzuki, Hiroaki Nishimatsu, Akira Ishikawa, Hirokazu Matsushita, Kazuhiro Kakimi, Yukio Homma., High expression of Heat Shock Protein 105 Predicts Favorable Prognosis in Bladder Cancer Patients Treated by a Radical Cystectomy.
• 2012/9/30-10/4, The 32nd Congress of the Societe Internationale d’Urokigue, Fukuoka,Japan, Yutaka Enomoto, Haruki Kume, Hiroshi Fukuhara, Tetsuya Fujimura, Motofumi Suzuki, Hiroaki Nishimatsu, Akira Ishikawa, Hirokazu Matsushita, Kazuhiro Kakimi, Yukio Homma., Dendritic Cell-based Immunotherapy Combined with Sunitinib for Metastatic Renal Cell Carcinoma.
• 2012/9/15, The 9th Catholic International Stem Cell Symposium: step up to Translational Research, Seoul, Korea. Kazuhiro Kakimi. Autologous γδT cell transfer therapy for the treatment of Solid Cancer
• 2013/1/30, Keystone Symposia on Molecular and Cellular Biology「Cancer Immunology and Immunotherapy」Vancouver, British Columbia, Canada, Kazuhiro Kakimi, Autologous γδT cell transfer therapy for the treatment of Solid Cancer

2011

• 2011/10/17-20. The 2nd Meeting of Asian Cellular Therapy Organizaiton 2011。Miyazaki, JAPAN. Kakimi K, Izumi T, Kondo M, Fujieda N, Kondo A, Tamura N, Maekawa R Requirement for comon g chain cytokines for adoptive transferred γδ T cell function and homeostasis in vivo.
• 2011/11/1. HAA-ISHAPD 2011; Sydney, Australia. (Symposium Invited) Kakimi K. Efficient cross-presentation of soluble exogenous antigens introduced into dendritic cells.

2010

• 2010/4/17-21, AACR 101st Annual Meeting 2010. Washington, DC. Kazuhiro Kakimi, Tomohiro Murakawa, Takeshi Fukami, Shigenori Goto, Toru Kaneko, Yukihiro Yoshida, Shin-ichi Takamoto, Jun Nakajima. Adoptive γδ T cell transfer for non-small cell lung cancer.
• 2010/8/22-27, 14th International Congress of Immunology. Kobe, Japan, Sakuta, K., Noguchi, A., Ariyhoshi, A., Nakata, J., Maekawa, R., Kakimi, K. Adoptive gamma/delta T cell for the treatment of cancer. 14th
• 2010/8/22-27, 14th International Congress of Immunology. Kobe, Japan, Kurachi, M., Suenaga, F., Kajiro, S., Ueha, S., Abe, J., Kakimi, K., Matushima, K. Chemokine receptor CXCR3 regulates the generation of memory CTL.
• 2010/8/22-27, 14th International Congress of Immunology. Kobe, Japan Ueha, S., Abe, J., Kakimi, K., Shono, Y., Wnag, Y., Hosoi, A., Kurachi, M., Matsushima,K., Dynamics of CCR7+ tumor-infiltrating dendritic cells that regulate anti-tumor immune response.
• 2010/8/22-27, 14th International Congress of Immunology. Kobe, Japan, Hosoi, A., Maekawa, R., Kakimi, K. CTL therapy-induced accumulation of CD11b+Gr-1+ myeloid-derived suppressor cells in tumor.
• 2011/2/12-17, 40th Keystone Symposia on Molecular and Cell Biology. Santa Fe, New Mexico, USA, Kazuhiro Kakimi, Akihiro Hosoi, hirokazu Matsushita., CTL therapy-induced accumulation of CD11b+Gr-1+ myeloid -derived suppressor cells in tumors.
• 2011/3/16, Immunology 2011: 98th Annual Meeting The American Association of Immunologist 2011. San Francisco, CA, USA. Kakimi K, Izumi T, Kondo M, Fujieda N, Kondo A, Morishita T, R.Maekawa, Matsushita H: Requirement for common g chain family cytokines for adoptive transferred γδ T cell function and homeostasis in vivo.

2009

• 2009/10/20. 22nd European Association for Cardio-Thoracic Surgery (EACTS), Wien, Austria, Oral presentation Nakajima J, Kakimi K, Murakawa T, Fuakami T, Yoshida T, Takamoto S. Adoptive immunotherapy for recurrent non-small cell lung cancer patients with autologous gammadelta T cells.

2008

• 2008/4/13. AACR Annual meeting San Diego, CA. USA. Kazuhiro Kakimi, Akihiro Hosoi, Yayoi Takeda, Ryuji Maekawa, Kiyoshi Takatsu. Efficient expansion and activation of tumor-specific CTLs by transcutaneous CTL and Th1 epitope peptide immunization with TLR7 ligand.

2007

• 2007/11/2-6. The 58th ANNUAL MEETING OF THE AMERICAN ASSOCIATION FOR THE STUDY OF LIVER DISEASES. Kiminori Kimura, Masahito Nagaki, Kazuhiro Kakimi, Hisataka Moriwaki. Critical Role of CD44 in Hepatotoxin-mediated Liver Injury

2006

• 2006/5/12-16. Immunology 2006, Annual Meeting of The American Association of Immunologists. Saito A., Kakimi K., Motomura N., Takamoto S.. Restriction of methicillin-resistant Staphylococcus aureus growth in allogeneic vascular grafts by indoleamie 2’3-dioxygenase.
• 2006/6/1-3. The 14th Annual Meeting of the Asian Society for Cardiovascular Surgery. Saito A, Motomura N, Kakimi K, Ono M, Takai D, Takamoto S. Cryopreservation does not influence the allogenicity and the progression of vasculopathy in post-transplant rat aortas.
• 2006/7/22-27. The 2006 World Transplant Congress. Saito A, Kakimi K, Motomura N, Noguchi M, Takai D, Narui K, Ueha S, Ssasatsu M, Takamoto S. Vascular allografts are resistant to methicillin-resistant Staphylococcus Aureus infection by Indoleamine 2' 3' - Dioxygenase in rat aortic transplant model.